Research Applications
Joint Health
Preliminary studies suggest improvements in joint comfort and function, attributed to collagen peptides and GAGs.
Gut Health
Glutamine and gelatin content may support intestinal barrier integrity, though clinical evidence is limited.
General Nutrition
Provides bioavailable collagen amino acids (glycine, proline, hydroxyproline) often underrepresented in modern diets.
Mechanism of Action
The collagen peptides in bone broth (Pro-Hyp, Hyp-Gly) activate fibroblast and chondrocyte collagen synthesis through matrikine signaling. GAGs (chondroitin, glucosamine) support cartilage matrix hydration and joint lubrication. Glycine and proline provide substrate for endogenous collagen synthesis. Glutamine supports intestinal epithelial integrity.
Biological Pathways
Collagen matrikine signaling. GAG-mediated cartilage hydration. Glutamine for intestinal tight junction maintenance. Mineral absorption for bone health.
Dosage Information
Calculation Results
Syringe Fill Level (100u syringe)
Protocols
No protocols featuring this peptide yet.
Browse All ProtocolsStability & Storage
Liquid bone broth: store frozen or refrigerated (3-5 days). Powdered bone broth protein: stable at room temperature for 1-2 years. Sensitive to microbial contamination in liquid form.
Side Effects & Precautions
Generally well-tolerated. Heavy metal contamination (lead) has been detected in some bone broth products — quality sourcing is important. GI discomfort if high in histamine. Allergic reactions to source animal proteins possible.
Research Use Only. This information is for educational and research purposes only. Not intended for medical advice or self-medication.
Regulatory Status
Food product / dietary supplement. GRAS status. No drug claims. Available worldwide.
Research Studies
Bone Broth: Nutritional Content and Clinical Implications
Mar-Solís LM, Soto-Domínguez A, Rodríguez-Tovar LE, et al.
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