Bone Broth Peptides molecular structure
Bone Broth Peptides molecular structure
Approved
🧴Cosmetic & Topical

Bone Broth Peptides

Also known as: Bone Broth Protein

Routes

1 route

Bone broth peptides are a complex mixture of bioactive peptides, amino acids, minerals, and glycosaminoglycans (GAGs) derived from slow-cooking animal bones and connective tissues. The extended cooking process (12-48 hours) hydrolyzes collagen, releasing peptide fragments along with gelatin, chondroitin sulfate, glucosamine, hyaluronic acid, and bone-derived minerals (calcium, magnesium, phosphorus). While bone broth has been consumed for millennia in traditional cuisines worldwide, modern scientific interest focuses on its collagen peptide content and the synergistic effects of its multiple bioactive components. Commercial bone broth protein supplements typically provide 15-20g protein per serving with a collagen-rich amino acid profile. Clinical evidence for bone broth is less robust than for purified collagen peptides, as the variable composition makes standardization challenging.

Research Use OnlyFor educational and research purposes only

Research Applications

Joint Health

Preliminary studies suggest improvements in joint comfort and function, attributed to collagen peptides and GAGs.

Gut Health

Glutamine and gelatin content may support intestinal barrier integrity, though clinical evidence is limited.

General Nutrition

Provides bioavailable collagen amino acids (glycine, proline, hydroxyproline) often underrepresented in modern diets.

Mechanism of Action

The collagen peptides in bone broth (Pro-Hyp, Hyp-Gly) activate fibroblast and chondrocyte collagen synthesis through matrikine signaling. GAGs (chondroitin, glucosamine) support cartilage matrix hydration and joint lubrication. Glycine and proline provide substrate for endogenous collagen synthesis. Glutamine supports intestinal epithelial integrity.

Biological Pathways

Collagen matrikine signaling. GAG-mediated cartilage hydration. Glutamine for intestinal tight junction maintenance. Mineral absorption for bone health.

Dosage Information

Typical dosage ranges for research applications. Always verify with current literature.
Typical Dose
10,000,000 mcg
Dose Range
2,500,000 - 15,000,000 mcg
Frequency
Once daily
Dosage Calculator
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Dosage calculation parameters
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Body weight input
Recommended dose per kg
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Desired dose input
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Calculation Results

Concentration
2.5 mg/ml
Dose Volume
0.1 ml0.100 ml
Insulin Syringe
10 units
Doses per Vial
2020 doses @ 250 mcg

Syringe Fill Level (100u syringe)

05010010.0uunits
0u10.0 / 100 units (10%)100u

Protocols

No protocols featuring this peptide yet.

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Stability & Storage

Liquid bone broth: store frozen or refrigerated (3-5 days). Powdered bone broth protein: stable at room temperature for 1-2 years. Sensitive to microbial contamination in liquid form.

Side Effects & Precautions

Generally well-tolerated. Heavy metal contamination (lead) has been detected in some bone broth products — quality sourcing is important. GI discomfort if high in histamine. Allergic reactions to source animal proteins possible.

Research Use Only. This information is for educational and research purposes only. Not intended for medical advice or self-medication.

Regulatory Status

Approved

Food product / dietary supplement. GRAS status. No drug claims. Available worldwide.

Research Studies

Bone Broth: Nutritional Content and Clinical Implications

Mar-Solís LM, Soto-Domínguez A, Rodríguez-Tovar LE, et al.

Journal of Medicinal Food
2021
View Source
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